Complete Up To Date Information about Advantage DUO.
NADA Number: 141-208 | |
| Proprietary Name |
Advantage® DUO |
|---|---|
| Sponsor |
Bayer Healthcare LLC, Animal Health Division |
| Sponsor Address |
P. O. Box 390 Sahwnee Mission, KS 66201 USA |
| Ingredients |
Imidacloprid Ivermectin |
| Species |
Dog, no use class stated or implied |
| Routes of Administration |
Topical |
| Dose Form |
Liquid (solution) |
| Drug Form |
Liquid (solution) |
| Dispensing Status |
RX |
| Exclusivity |
Granted for the prevention of heartworm disease caused by Dirofilaria immitis for the treatment of flea infestations (Ctenocephalides felis). |
|
Dosage Amount, Indications & Limitations |
524.1140 Imidacloprid and ivermectin. Specifications. The product is available in unit applicator tubes containing 0.4, 1.0, 2.5, or 4.0 milliliters. Each milliliter of solution contains 100 milligrams imidacloprid and 800 micrograms ivermectin. Conditions of Use Dogs Amount. The recommended minimum dosage is 4.5 milligram per pound (10 milligram per kilogram) of imidacloprid and 36.4 micrograms per pound (80 micrograms per kilogram) of ivermectin, topically once a month. Indications: For the prevention of heartworm disease caused by Dirofilaria immitis; kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). Limitations. Federal law restricts this drug to use by or on the order of a licensed veterinarian. |
| Tolerances |
A tolerance is established for 22,23-dihydroavermectin B1a (marker residue) in liver (target tissue) as follows: a. In cattle 100 parts per billion. b. In swine 20 parts per billion. c. In sheep 30 parts per billion. d. In reindeer 15 parts per billion. e. In American bison 15 parts per billion. Muscle residues are not indicative of the safety of other edible tissues. A tolerance is established for 22,23-dihydroavermectin B1a (marker residue) in muscle as follows: a. Swine 20 parts per billion b. Cattle 10 parts per billion |