520.622d Diethylcarbamazine citrate capsules.

Specifications: Each capsule contains either 12.5, 50, 200, or 400 milligrams of diethylcarbamazine citrate.

Conditions of use:

Dogs

Amount: 3 milligrams per pound of body weight daily. Administer orally directly or added to the daily ration.

Indications: For prevention of heartworm disease (Dirofilaria immitis) in dogs

Limitations: Do not treat dogs with established heartworm infections until they have been converted to a negative status by the use of adult-cidal and microfilaricidal drugs. Inadvertent administration to heartworm-infected dogs may cause adverse reactions due to pulmonary occlusion or shock. Overdosage may cause emesis. For prevention of heartworm disease in heartworm-endemic areas, administration of the drug should begin 1 month before and continue 2 months after the mosquito season. Dogs receiving prophylactic therapy should be examined every 6 months for the presence of microfilariae. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Amount: 25 to 50 milligrams per pound of body weight in a single dose. Administer orally directly or added to the daily ration.

Indications: As an aid in treatment of ascarid infections in dogs (Toxocara canis and Toxascaris leonina).

Limitations: For ascarid infections, repeat treatment in 10 to 20 days to remove immature worms that may enter the intestine the lungs after the first dose. Do not treat dogs with established heartworm infections until they have been converted to a negative status by the use of adult-cidal and microfilaricidal drugs. Inadvertent administration to heartworm-infected dogs may cause adverse reactions due to pulmonary occlusion or shock. Overdosage may cause emesis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.