Complete Up To Date Information about Estrumate .
NADA Number: 113-645 | |
| Proprietary Name |
Estrumate® |
|---|---|
| Sponsor |
Schering-Plough Animal Health Corp. |
| Sponsor Address |
P.O. Box 21 Sandown Village, NJ 3171 VIC Australia |
| Ingredients |
Cloprostenol Sodium |
| Species |
Cattle, dairy, cows and heifers (female breeding stock) Cattle, beef, heifers fed in confinement for slaughter Cattle, beef, cows and heifers (female breeding stock) |
| Routes of Administration |
Intramuscular |
| Dose Form |
Liquid (solution) |
| Drug Form |
Liquid (solution) |
| Dispensing Status |
RX |
| Patent Number |
4321275 |
|
Dosage Amount, Indications & Limitations |
522.460 Cloprostenol sodium. Specifications: Each milliliter of the aqueous solution contains 263 micrograms of cloprostenol sodium (equivalent to 250 micrograms of cloprostenol) in a sodium citrate, anhydrous citric acid and sodium chloride buffer containing 0.1 percent w/v chlorocresol B.P. as a bactericide. Conditions of use: Cattle (beef and dairy) Amount: 2 milliliters (equivalent to 500 micrograms of cloprostenol). Double cloprostenol injection. Give cattle a second injection 11 days after the first injection. For intramuscular use. Indications: To induce luteolysis. For scheduling estrus and ovulation to control the time at which cycling cows or heifers can be bred. Limitations: Estrus should occur 2 to 5 days after the second injection, and cattle should be inseminated at the usual time relative to the detection of estrus. If estrus is not observed, treated animals may be inseminated either once at about 72 hours post injection or twice at 72 and 96 hours following the second injection. Do not administer to pregnant animals where the calf is not to be aborted. Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. Cloprostenol is readily absorbed through the skin and may cause abortion and/or bronchiospasms. Accidental spillage on the skin should be washed off immediately soap and water. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Amount: 2 milliliters (equivalent to 500 micrograms of cloprostenol). Single cloprostenol injection. Indications: For terminating unwanted pregnancies from mis-matings from 1 week after mating until 5 months after conception, or for treating unobserved (non-detected) estrus, mummified fetus, and luteal cysts. Single cloprostenol injection for the treatment of pyometra. Limitations: Treat only animals with a mature corpus luteum. Estrus should occur in 2 to 5 days and cattle should be inseminated at the usual time relative to the detection of estrus. If estrus is not observed, treated animals may be inseminated either once at 72 hours post injection or twice at 72 and 96 hours post injection. Do not administer to pregnant animals where the calf is not to be aborted. Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. Cloprostenol is readily absorbed through the skin and may cause abortion and/or bronchiospasms. Accidental spillage on the skin should be washed off immediately soap and water. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Specifications: Each milliliter of sterile aqueous solution contains 131.5 micrograms of cloprostenol sodium (equivalent to 125 micrograms of cloprostenol). Conditions of use: Cattle (feedlot heifers) Amount: 3 milliliters (equivalent to 375 micrograms of cloprostenol) intramuscularly per animal as a single dose. Indications: To induce abortion in pregnant feedlot heifers from 1 week after mating until 4 1/2 months of gestation. Limitations: Federal law restricts this drug to use by or on the order of a licensed veterinarian. |