Complete Up To Date Information about Syncro-Mate-B .
NADA Number: 134-930 | |
| Proprietary Name |
Syncro-Mate-B® |
|---|---|
| Sponsor |
Merial Ltd. |
| Sponsor Address |
3239 Satellite Blvd. Bldg. 500 Duluth, GA 30096-4640 USA |
| Ingredients |
Norgestomet Estradiol Valerate |
| Species |
Cattle, dairy, heifers not lactating Cattle, beef, cows and heifers (female breeding stock) |
| Routes of Administration |
Intramuscular Subcutaneous |
| Dose Form |
Implant Liquid (solution) |
| Drug Form |
Implant Liquid (solution) |
| Dispensing Status |
OTC |
| Patent Number |
3860701 3892855 3941880 3946106 3992518 4053580 |
|
Dosage Amount, Indications & Limitations |
522.850 Estradiol valerate and norgestomet in combination. Specifications: The product is a two-component drug consisting of an implant containing 6.0 milligrams of norgestomet and an injectable solution (sesame oil) containing 3.0 milligrams of norgestomet and 5.0 milligrams of estradiol valerate per 2 milliliters. Conditions of use: Cattle Amount: One implant and 2 milliliters of injection at time of implantation. Insert implant subcutaneously in the ear. Indications: For synchronization of estrus/ovulation in cycling beef cattle and non-lactating dairy heifers. Limitations: Then immediately inject solution intramuscularly only. Counting the day of implantation as day 1, remove the implant on day 10. Collect all implants as they are removed and burn them. While animals are restrained for artificial insemination, avoid other treatments such as vaccinations, dipping, pour-on grub and louse prevention, spraying, etc. When inseminating without estrus detection the entire treated group should be started at 48 hours after the last implant has been removed and should be completed within 6 hours. Where estrus detection is preferred, insemination should be approximately 12 hours after first detection of estrus. Those that do not conceive can be re-bred when they return to estrus approximately 17 to 25 days after implant removal. Do not use in cows producing milk for human consumption. |
| Tolerances |
No residues of estradiol, resulting from the use of estradiol or any of the related esters, are permitted in excess of the following increments above the concentrations of estradiol naturally present in untreated animals: a. In uncooked edible tissues of heifers, steers, and calves: (1) 120 parts per trillion for muscle (2) 480 parts per trillion for fat (3) 360 parts per trillion for kidney (4) 240 parts per trillion for liver b. In uncooked edible tissues of lambs: (1) 120 parts per trillion for muscle (2) 600 parts per trillion for fat, kidney, and liver |